No pain, big gain: partnership sends Mesoblast shares soaring

Original article by Damon Kitney
The Australian – Page: 21 : 11-Sep-19

Shares in Melbourne-based stem cell developer Mesoblast rose by over 22 per cent on 10 September after it announced details of a strategic partnership with German drug company Grunenthal. The partnership will see the two companies work to develop and commercialise a cell therapy to threat severe lower back pain, with Mesoblast receiving up to $US150 million ($218.56 million) in upfront and milestone payments prior to the launch of any product developed under the partnership. Billionaire Alex Waislitz, who is one of Mesoblast’s investors, suggests the global potential for a non-opiate product for treating lower back pain could be worth "many billions of dollars" each year.

CORPORATES
MESOBLAST LIMITED – ASX MSB, GRUNENTHAL GMBH

CSL buys way into cell, gene therapy

Original article by Sarah-Jane Tasker
The Australian – Page: 19 : 29-Aug-17

CSL has announced that it will spend $US91 million ($A114 million) on the purchase of US-based biotechnology company Calimmune. CSL executive Andrew Nash says the purchase of Calimmune gives it access to skills and technologies in the area of gene and cell-based therapies that it does not currently have. He said that CSL has had its eye on Calimmune, which has operations in both the US and Australia, for about a year.

CORPORATES
CSL LIMITED – ASX CSL, CALIMMUNE INCORPORATED

CSL shrugs off growth concerns, shares slide

Original article by Ben Potter
The Australian Financial Review – Page: 17 & 22 : 18-Aug-16

CSL has posted a 2015-16 net profit of $US1.24bn ($A1.6bn), which is 10 per cent lower than previously. The blood products and vaccines group’s sales rose by eight per cent to $US6.13bn. Earnings per share fell by eight per cent to $US2.69, but increased by seven per cent on a constant currency basis. CSL has forecast underlying net profit and EBITDA growth of 11 per cent and 14 per cent respectively in 2016-17. Its shares closed five per cent lower at $A110.84 on 17 August 2016.

CORPORATES
CSL LIMITED – ASX CSL, SHIRE PHARMACEUTICALS GROUP PLC, NOVARTIS AG, CSL BEHRING, WILSONS ADVISORY AND STOCKBROKING LIMITED, SEQIRUS PTY LTD

Mesoblast falls 42pc as investors lose heart

Original article by Jessica Gardner, James Thomson
The Australian Financial Review – Page: 13 & 18 : 15-Jun-16

The market capitalisation of Australian biotechnology group Mesoblast has fallen to $A750m following a 42.2 per cent fall in its share price on 14 June 2016. The stock closed at a seven-year low of $A1.11 after Teva Pharmaceutical Industries advised that it will not finance the final round of clinical trials for Mesoblast’s stem-cell treatment for heart failure. Mesoblast had cash reserves of around $US100m at the end of the March quarter, and CEO Silviu Itescu is confident that the group can secure funding partners before its cash reserves are exhausted.

CORPORATES
MESOBLAST LIMITED – ASX MSB, TEVA PHARMACEUTICAL INDUSTRIES LIMITED, CEPHALON INCORPORATED, CANACCORD GENUITY (AUSTRALIA) LIMITED

Focus on sales reboots growth at Cochlear

Original article by Tim Binsted
The Australian Financial Review – Page: 15 : 12-Feb-16

Australian-listed Cochlear has posted a 2015-16 interim net profit of $A94m, which is 32 per cent higher than previously. Revenue also increased by 32 per cent, to $A581.7m, and sales of its hearing implants rose by 26 per cent to 14,748 units. CEO Chris Smith says the group has benefited from its consumer-focused strategy, and notes that the 65-plus age group represents a huge growth opportunity for Cochlear.

CORPORATES
COCHLEAR LIMITED – ASX COH

Biotech index outperformance in 2015 points to opportunities

Original article by Jessica Sier
The Australian Financial Review – Page: 18 : 8-Jan-16

Australia’s benchmark S&P/ASX 200 Index shed 2.7 per cent during 2015. However, an index of 40 biotechnology companies which was compiled by "Biotech Daily" gained 22 per cent. ImpediMed, Opthea, Nanosonics, Starpharma and Mesoblast are among the biotechnology stocks that could potentially perform well in 2016.

CORPORATES
STANDARD AND POOR’S ASX 200 INDEX, BIOTECH DAILY, IMPEDIMED LIMITED – ASX IPD, OPTHEA LIMITED – ASX OPT, NANOSONICS LIMITED – ASX NAN, STARPHARMA HOLDINGS LIMITED – ASX SPL, MESOBLAST LIMITED – ASX MSB, HATCHTECH PTY LTD, SPINIFEX PHARMACEUTICALS PTY LTD, FIBROTECH THERAPEUTICS PTY LTD, QRXPHARMA LIMITED – ASX QRX, OSPREY MEDICAL INCORPORATED – ASX OSP, GI DYNAMICS INCORPORATED – ASX GID, CANACCORD GENUITY (AUSTRALIA) LIMITED, COCHLEAR LIMITED – ASX COH, CSL LIMITED – ASX CSL, RESMED INCORPORATED – ASX RMD

Biotech founder Itescu loses $90m in morning as US float disappoints

Original article by Tim Binsted
The Australian Financial Review – Page: 19 : 17-Nov-15

Mesoblast expects to raise $US63.8 million ($A95.8 million) by issuing American Depositary Shares (ADSs) in the US. The Australian-listed stem cell therapy group is offering ADSs at $US8 a unit, which implies that Mesoblast has a valuation of $A2.20 a share on the Australian stock exchange. Mesoblast shares declined 38.4 per cent to $A2.10 on 16 November 2015.

CORPORATES
MESOBLAST LIMITED – ASX MSB, NASDAQ, STARPHARMA HOLDINGS LIMITED – ASX SPL

CSL urges lower manufacturing tax

Original article by Jennifer Hewett
The Australian Financial Review – Page: 2 : 4-Aug-15

CSL is one of Australia’s most successful companies. It is a global player in the field of biotechnology. CFO Gordon Naylor complains about high tax rates in Australia which, he believes, hinder the development of the country’s advanced manufacturing sector. CSL advocates the introduction of a new tax rate of 10 per cent for advanced manufacturing. Under the current tax regime, Australian companies pay 30 per cent in corporate tax.

CORPORATES
CSL LIMITED – ASX CSL, BLOOMBERG LP, AUSTRALIA. DEPT OF INDUSTRY AND SCIENCE

Slash company tax rate, CSL urges

Original article by Joanna Mather
The Australian Financial Review – Page: 6 : 16-Jun-15

CSL’s CFO Gordon Naylor says the blood products group does not intend to reduce its manufacturing presence in Australia. However, he has conceded that CSL would have seriously considered building a $A500m plant in Australia if the nation’s 30 per cent corporate tax rate had been more competitive. CSL opted to build the facility in Switzerland, which has a company tax rate of 18 per cent. CSL has suggested that Australia adopt a tax rate of 10 per cent for advanced manufacturers.

CORPORATES
CSL LIMITED – ASX CSL, CORPORATE TAX ASSOCIATION, MINERALS COUNCIL OF AUSTRALIA, ORGANISATION FOR ECONOMIC CO-OPERATION AND DEVELOPMENT

Diabetes trial success

Original article by Tim Binsted
The Australian Financial Review – Page: 22 : 9-Jun-15

Listed biotechnology group Mesoblast has reported encouraging results from the phase two trial of a treatment for diabetic nephropathy. CEO Silviu Itescu says nearly two million people had the diabetes-related kidney disease in 2013. The clinical trial found that the stem cell-based treatment showed that participants had improved kidney function and experienced no adverse side-effects.

CORPORATES
MESOBLAST LIMITED – ASX MSB, AMERICAN DIABETES ASSOCIATION, CELGENE INCORPORATED, SIRTEX MEDICAL LIMITED – ASX SRX