MEDICINE – RESEARCH – GREAT BRITAIN

Early blood test to predict dementia is step closer as biological markers identified

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Original article by Ian Sample
The Guardian – Page: Online : 13-Feb-24

Analysis of blood samples collected from over 50,000 healthy volunteers enrolled in the UK Biobank project has resulted in researchers identifying patterns of four proteins that predicted the onset of dementia. When combined with traditional risk factors such as age and gender, it has enabled the researchers to forecast dementia with an estimated 90% accuracy almost 15 years before people received clinical confirmation of the disease. With over 55 million people currently living with dementia worldwide, the research is seen as a major step towards developing a blood test that can predict dementia years before a formal diagnosis

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Key to controlling appetite revealed

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Original article by Bridie Smith
The Age – Page: 8 : 14-Jul-14

Scientists at the Florey Institute of Neuroscience & Mental Health in Melbourne and Cambridge University in the UK have established a function of the insulin-like peptide 5 (Insl5) molecule. Found in the human colon, it is now believed to be responsible for letting the brain know when the body needs food. A version of Insl5 has been created in the laboratory, and the research may lead to the development of appetite suppressants that can help those suffering from obesity. It may also aid those who have lost their appetite during treatment for cancer or AIDS. The findings are being published in the "PNAS" journal

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THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH, CAMBRIDGE UNIVERSITY, TAKEDA PHARMACEUTICAL COMPANY LIMITED